TABLE 1.
In vitro activities of mefloquine, chloroquine, quinine, pentamidine, and lincomycin against bovine and human B. divergens isolates
| Isolate source and isolate | MIC (μg/liter of blood)a
|
||||
|---|---|---|---|---|---|
| Meflo- quine | Chloro- quine | Quinine | Pent- amidine | Lincomycin | |
| Bovine isolates | |||||
| Muenchen | >24 | >48 | >96 | 5.1 ± 1 | 70,000 ± 2,100 |
| Weybridge 8843 | ND | ND | >96 | ND | ND |
| Taylor | >24 | >48 | >96 | 2.5 ± 0.4 | 32,000 ± 3,800 |
| Human isolates | |||||
| Le Mans | >24 | >48 | >96 | 2.2 ± 0.0 | 37,000 ± 4,700 |
| Rouen | ND | ND | >96 | ND | 38,000 ± 2,500 |
a
Results are for two to six triplicate experiments. ND, not determined.