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. 2022 Nov 10;52:19–28. doi: 10.1016/j.jare.2022.11.003

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© 2023 The Authors. Published by Elsevier B.V. on behalf of Cairo University.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — Gross pathology (A), light microscopy (B), electron microscopy observation (C), tubulointerstitial damage scores (D), and foot process fusion rates (E) of the kidney of hyperuricemic rats treated for 6 weeks with SFN. Scale bar: 100 μm; original magnification 400× (B); and scale bar: 5 μm; original magnification 3000× (C). Five fields of view per section and three rats per group were tested. * indicates that the difference is statistically significant compared with the NC group (P＜0.05); # indicates that the difference is statistically significant compared to the HUA group (P＜0.05); ANOVA, followed by LSD for post-hoc comparisons.