Table 2.
Combination of age, sex, BMI, ANGPT2, BMP10, FGF23 for prediction of prevalent AF.
| Model | C-statistic (95% CI) | Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | Positive predictive value (%, 95% CI) | Negative predictive value (%, 95% CI) |
|---|---|---|---|---|---|
| Apparent | 0.785 (0.756, 0.815) | 59.85 (54.94, 64.63) | 81.21 (77.61, 84.46) | 71.30 (67.17, 75.11) | 72.18 (69.60, 74.61) |
| Optimism-adjusted | 0.743 (0.712, 0.775) | 51.83 (47.03, 56.61) | 79.57 (75.98, 82.84) | 66.47 (62.18, 70.50) | 67.89 (65.54, 70.16) |
| Validation | 0.719 (0.677, 0.762) | 51.05 (45.10, 56.98) | 81.49 (76.70, 85.67) | 71.92 (66.38, 76.87) | 64.19 (61.16, 67.12) |
Performance measures of the apparent, optimism adjusted and validation models.
AF atrial fibrillation, BMI body mass index, ANGPT2 angiopoietin 2, BMP10 bone morphogenetic protein 10, FGF23 fibroblast growth factor 23.