TABLE 2.
Eradication of adherent bacteria of two isogenic strains of S. epidermidis in an in vitro and in an in vivo model
| Drug | No. of sterile beads/total no. of beads studied
|
|||
|---|---|---|---|---|
| In vitro model
|
In vivo model
|
|||
| RP62A | M7 | RP62A | M7 | |
| Amikacin | 0/25 | 0/25 | 0/24 | 6/24a |
| Levofloxacin | 9/25 | 21/25a | 1/24 | 8/24a |
| Rifampin | 22/25 | 25/25 | 8/24 | 18/24a |
| Teicoplanin | 0/25 | 0/25 | 0/24 | 5/24a |
a
The statistical significance of the eradication rate between the two strains was determined, and the difference was significant (P < 0.05).