Table 2.
Total number of granulomas observed at each stage and time point in guinea pig lungs.
| Days/weeks post-inoculation | Granuloma stage | Total count | |||
|---|---|---|---|---|---|
| I | II | III | IV | ||
| 5 dpi (n = 6) | 12 | 0 | 0 | 0 | 12 |
| 10 dpi (n = 6) | 9 | 0 | 0 | 0 | 9 |
| 3 wpi (n = 8)* | 9 | 28 | 14 | 0 | 51 |
| 4 wpi (n = 8)* | 126 | 130 | 37 | 0 | 293 |
| 8 wpi (n = 8)*,** | 185 | 209 | 8 | 16 | 418 |
| 24–27 wpi (n = 20)*,** | 346 | 458 | 48 | 40 | 892 |
dpi, days post infection; wpi, weeks post infection. *X-sq for trend p < 0.05 compared to 5 and 10 dpi and **X-sq for trend p < 0.05 compared to 3 and 4 wpi.