Table 3.
Total score for the number of AFB in granulomas at each stage and time point in the guinea pig lungs.
Granuloma stage | 5 dpi | 10 dpi | 3 wpi | 4 wpi | 8 wpi | 24–27 wpi | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | |
Stage I | 6 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 21 | 2 | 0 | 0 | 27 | 11 | 5 | 0 |
Stage II | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 2 | 8 | 0 | 0 | 17 | 9 | 0 | 0 | 24 | 23 | 3 | 10 |
Stage III | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 4 | 7 | 0 | 1 | 1 | 0 | 2 | 10 | 3 | 1 |
Stage IV | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 3 | 1 | 2 | 3 | 0 |
Total count | 6 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 2 | 2 | 1 | 2 | 7 | 10 | 4 | 7 | 38 | 15 | 4 | 3 | 54 | 46 | 14 | 11 |
The total number of AFBs present in each granuloma were counted and recorded using a scoring system: 0 = no AFBs, 1 = 1–10 AFBs, 2 = 11–50 AFBs, and 3 ≥ 50 AFBs. AFB, acid fast bacilli; dpi, days post infection; wpi, weeks post infection.