TABLE 2.

Effect of G-CSF on PMN activity against C. albicans Sh27: synergy with VCZ

Condition	VCZ concn (μg/ml)	Mean CFU ± SD	% Fungistasis	% Killing	P vs reference conditiona
					Inoculum	PMN alone	PMN + 0.01 μg of VCZ/ml
Inoculum		39,250 ± 6,200			—
CTCM	0	470,000 ± 12,500	0	0
	0.01	205,000 ± 22,500	57	0
PMN	0	29,000 ± 280	100	26	<0.05	—
	0.01	3,025 ± 920	100	93	<0.01		—
PMN + G-CSF (ng/ml)
100	0	2,930 ± 602	100	93	<0.01	<0.01
	0.01	2,400 ± 100	100	94	<0.01		NS
500	0	2,500 ± 800	100	94	<0.01	<0.01
	0.01	1,415 ± 200	100	96	<0.01		<0.05

^a—, row of data serving as reference for P values in column. NS, not significant (P > 0.05).