Table 1.

Baseline characteristics of study participants and statistical analysis results.

Variable	Number	Groups		Correlation analysis				logistic regression analysis
		IAV-related Death (n = 44)	Alive (n = 610)	p-value	OR	95% CI		B	S.E.	Wald	p-value	OR	95% CI
Age	71.9 ± 11.4	73.3 ± 11.4	71.8 ± 11.4	0.406	0.988	0.961	1.016	−0.024	0.017	2.064	0.151	0.976	0.944	1.009
Sex				0.148	0.630	0.336	1.179	−0.767	0.359	4.556	0.033*	0.464	0.230	0.939
Female	322	17	305
Male	332	27	305
History of Diseases
Cadiovascular/Cerebrovascular disease	362	27	335	0.407	1.304	0.696	2.442	0.312	0.356	0.766	0.381	1.366	0.680	2.743
Neuromuscular disease	31	1	30	0.437	0.450	0.060	3.377	−0.889	1.072	0.688	0.407	0.411	0.050	3.360
Respiratory disease	168	11	157	0.914	0.962	0.475	1.949	−0.112	0.393	0.081	0.776	0.894	0.414	1.933
Liver/Kidney disease	167	15	152	0.181	1.559	0.814	2.985	0.446	0.380	1.375	0.241	1.561	0.741	3.288
Cancer	96	8	88	0.498	1.318	0.593	2.930	0.312	0.433	0.519	0.471	1.366	0.584	3.194
Autoimmune disease	14	1	13	0.950	1.068	0.136	8.357	0.365	1.108	0.108	0.742	1.440	0.164	12.624
Smoking status				0.318	0.670	0.305	1.472	−0.761	0.440	2.993	0.084	0.467	0.197	1.106
Current smoker	160	8	152
Never or former smoker	494	36	458
Number of Chronic diseases	2.3 ± 0.9	2.4 ± 0.8	2.3 ± 0.9	0.270	0.824	0.584	1.162
Glucose	189.2 ± 101.3	204.7 ± 120.6	188.0 ± 99.8	0.294	0.999	0.996	1.001	−0.002	0.001	1.766	0.184	0.998	0.995	1.001
Flu Vaccination*	438	23	415	0.034*	0.515	0.278	0.952	−0.972	0.362	7.228	0.007*	0.378	0.186	0.768
S.Pneumoniae vaccination	269	20	249	0.547	1.208	0.653	2.235	0.343	0.367	0.872	0.351	1.409	0.686	2.896
Type of influenza Virus
Influenza A virus	540	34	506	0.340	1.431	0.686	2.987	0.496	1.179	0.177	0.674	1.641	0.163	16.538
Influenza B virus	123	11	112	0.279	1.482	0.727	3.022	0.792	1.141	0.482	0.488	2.209	0.236	20.691
Anti-viral drug	609	40	569	0.550	0.721	0.246	2.112	−0.366	0.602	0.371	0.543	0.693	0.213	2.254
Anti-biotics	571	44	527	0.997	134878355	0.000	.
Hyperlipidemia medications
IStatin	238	14	224	0.515	0.804	0.418	1.549	−0.191	0.365	0.275	0.600	0.826	0.404	1.688
INon-statin	15	1	14	0.992	0.990	0.127	7.708	0.270	1.087	0.062	0.804	1.309	0.156	11.016
Antidiabetic drugs
IMetformin*	314	14	300	0.029*	0.482	0.251	0.927	−0.966	0.401	5.811	0.016*	0.380	0.173	0.835
INon-metformin	115	6	109	0.062	0.385	0.141	1.048	−0.907	0.529	2.943	0.086	0.404	0.143	1.138
IInsulin	158	11	147	0.893	1.050	0.518	2.129	−0.531	0.443	1.438	0.230	0.588	0.247	1.401

OR, odd ratio; CI, confidence interval.

*indicated statistically significant (p-value <0.05).