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. 2023 Sep 26;9(10):e20428. doi: 10.1016/j.heliyon.2023.e20428

Table 8.

Chalcone derivatives investigated against HBV.

Compound(s) “Chemical name(s)” Virus subtype Study model(s) Results Inhibition mechanism Ref.
Glabaarachalcone and Isopongachromene “2-(1,3-benzodioxol-5-yl)-6-methoxy-8,8-dimethylpyrano[2,3-h]chromen-4-one” HBV In vitro, In silico Docking scores: 9.523 and −9.094 against HBV DNA polymerase, respectively Binding to the DNA polymerase of HBV [120]

HBV: Hepatitis B virus.