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. 2023 Sep 22;14:1263618. doi: 10.3389/fphar.2023.1263618

TABLE 5.

Comparison of clinical outcomes of patients with positive multi-drug resistant organism.

AMS (n = 58) Pre-AMS (n = 90) p-value
Primary outcomes
Use of Polymyxin (≥2 days), n (%) 9 (15.52) 28 (31.11) 0.034
DOT of Polymyxin (day/patients), mean (SD) 11.00 ± 5.07 13.18 ± 7.64 0.431
Use of Tigecycline (≥2 days), n (%) 2 (3.45) 10 (11.11) 0.127
DOT of Tigecycline (day/patients), mean (SD) 5.00 ± 2.83 8.50 ± 5.91 0.445
Secondary outcomes, n (%)
Mortality 13 (22.41) 24 (26.67) 0.698
All-cause readmission 7 (12.07) 4 (4.4) 0.111
Readmission due to the same cause as the previous admission 2 (3.45) 0 (0) 0.152
Prescription adjustment number (mean, IQR),items 3 (3,4) 2 (2,3) <0.001
Appropriate de-escalation 23 (39.66) 18 (20.00) <0.001
Adverse drug reactions 7 (12.07) 18 (20%) 0.264