TABLE 5.
Comparison of clinical outcomes of patients with positive multi-drug resistant organism.
| AMS (n = 58) | Pre-AMS (n = 90) | p-value | |
|---|---|---|---|
| Primary outcomes | |||
| Use of Polymyxin (≥2 days), n (%) | 9 (15.52) | 28 (31.11) | 0.034 |
| DOT of Polymyxin (day/patients), mean (SD) | 11.00 ± 5.07 | 13.18 ± 7.64 | 0.431 |
| Use of Tigecycline (≥2 days), n (%) | 2 (3.45) | 10 (11.11) | 0.127 |
| DOT of Tigecycline (day/patients), mean (SD) | 5.00 ± 2.83 | 8.50 ± 5.91 | 0.445 |
| Secondary outcomes, n (%) | |||
| Mortality | 13 (22.41) | 24 (26.67) | 0.698 |
| All-cause readmission | 7 (12.07) | 4 (4.4) | 0.111 |
| Readmission due to the same cause as the previous admission | 2 (3.45) | 0 (0) | 0.152 |
| Prescription adjustment number (mean, IQR),items | 3 (3,4) | 2 (2,3) | <0.001 |
| Appropriate de-escalation | 23 (39.66) | 18 (20.00) | <0.001 |
| Adverse drug reactions | 7 (12.07) | 18 (20%) | 0.264 |