Table 3A.
T cell Interactions with Macrophages and Fibroblasts following Immunization with Recombinant HRS.
| Cell Comparison | T cell–adaptive | T cell–innate | Macrophages* | Fibroblasts* |
|---|---|---|---|---|
| B6 WT | + | + | 1>2>6 | 8>13 = 21>18 = 5 = 7 = 10 |
| RAG1 KO | - | - | 6>2>1 | 13>8>5>10>7 = 18 = 21 |
| B6 WT | + | + | 1>2>6 | 8>21 = 13>18>5 = 7 = 10 |
| OT-II | - | + | 2>6>1 | 5>10>13>7 = 8>18>21 |
| MyD88fl/fl (Cre-) | + | + | 1>2>6 | 8>21 = 13>18 = 5 = 7 = 10 |
| CD4-Cre.MyD88fl/fl | + | - | 6>2>1 | 13>8>18>10 = 5 = 7 = 21 |
*relative ranking by number of cells per cluster.
Key macrophage and fibroblast cell clusters distinguishing B6 WT mice from designated mutant strains are highlighted in red.