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. 2023 Sep 22;14:1238221. doi: 10.3389/fimmu.2023.1238221

Table 3A.

T cell Interactions with Macrophages and Fibroblasts following Immunization with Recombinant HRS.

Cell Comparison T cell–adaptive T cell–innate Macrophages* Fibroblasts*
B6 WT + + 1>2>6 8>13 = 21>18 = 5 = 7 = 10
RAG1 KO - - 6>2>1 13>8>5>10>7 = 18 = 21
B6 WT + + 1>2>6 8>21 = 13>18>5 = 7 = 10
OT-II - + 2>6>1 5>10>13>7 = 8>18>21
MyD88fl/fl (Cre-) + + 1>2>6 8>21 = 13>18 = 5 = 7 = 10
CD4-Cre.MyD88fl/fl + - 6>2>1 13>8>18>10 = 5 = 7 = 21

*relative ranking by number of cells per cluster.

Key macrophage and fibroblast cell clusters distinguishing B6 WT mice from designated mutant strains are highlighted in red.