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. 2023 Sep 22;13:1265631. doi: 10.3389/fonc.2023.1265631

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Copyright © 2023 Li, Ding, Zheng, Xu, Li, Zhu, Zhang, Ma, Zhang, Zhong, Liang, Han, Zhang, He and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Numbers of ELN for overall early-stage EOC and HGSOC. (A, E) LOESS fitting curves based on ORs in ascending order of the number of ELN for early-stage EOC and HGSOC. (B, F) LOESS fitting curves based on exp (Coef) in ascending order of the number of ELN for early-stage EOC and HGSOC. (C, G) LOESS fitting curves based on HRs in ascending order of the number of ELN for early-stage EOC and HGSOC. ELN structural breakpoints for node stage migration, PLN and DSS based on Chow test are shown as blue lines in (A–C) and (E–G). (D, H) Kaplan-Meier plots for DSS based on ELN structural breakpoints of early-stage EOC and HGSOC. (I) Log-rank test P values for DSS of different ELN subgroups. P values less than 0.016 are statistically significant.