Table 3.

Associations of ELN (as a continuous variable) with Stage Migration, PLN and DSS in HGSOC with stage T1M0.

	Node Stage Migration (Logistica)			Positive Lymph Node (Linearb)			Disease-Specific Survival (Coxc)
	OR	95% CI	P OR	Coef	95% CI	P coef	HR	95% CI	P HR
ELN	1.014	1.004~1.024	0.007	0.017	0.012~0.022	< 0.001	0.990	0.981~0.998	0.012
Age			0.010	-0.027	-0.083~0.028	0.330			< 0.001
≤ 50	1						1
50 ~ 60	0.520	0.355~0.763	0.001				0.407	0.314~0.527	< 0.001
60 ~ 70	0.707	0.505~0.989	0.043				0.560	0.446~0.702	< 0.001
> 70	0.691	0.481~0.992	0.045				0.660	0.522~0.835	0.001
T stage			0.097	0.008	-0.054~0.070	0.798			< 0.001
T1a	1						1
T1b	0.747	0.556~1.002	0.052				0.675	0.557~0.819	< 0.001
T1c	1.164	0.786~1.723	0.448				0.642	0.468~0.879	0.006
N stage				3.239	3.051~3.426	< 0.001			< 0.001
N0							1
N1							0.515	0.413~0.643
Laterality			< 0.001	0.036	-0.043~0.114	0.372			0.391
Left	1						1
Right	0.436	0.300~0.633	< 0.001				0.835	0.650~1.073	0.158
Bilateral	0.623	0.437~0.889	0.009				0.842	0.658~1.077	0.171
Primary Site			0.006	0.308	0.122~0.495	0.001			0.536
Ovary	1						1
Fallopian tube	0.599	0.415~0.862					1.100	0.813~1.490
Differentiation			0.044	-0.005	-0.147~0.138	0.948			< 0.001
Grade 2	1						1
Grade 3&4	0.702	0.497~0.991					0.662	0.528~0.830

^a A linear relationship existed between ELN and logit N stage, variance inflation factors between independent variables were less than 10.

^b Residuals with uniform variances were approximately normally distributed and had no autocorrelation. Correlation coefficients between independent variables were less than 0.7 and variance inflation factors were less than 10.

^c Covariates violating the proportional hazards assumption were added as time-dependent covariates in the Cox regression models.

All p values less than 0.05 with statistical significance were use bold fronts.