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. 2023 Oct 5;6(12):e202302148. doi: 10.26508/lsa.202302148

Figure 1. HIV-1 infection induces M1 polarization of macrophages.

Figure 1.

(A) Morphologic features of monocyte-derived macrophages (MDMs) after HIV-1 infection for 1–3 d. Scale bar, 100 μm. (B, C) Changes in mRNA (B) and protein expressions (C) of M1 and M2 polarization markers in MDMs after HIV-1 infection for 1–3 d. (Statistical analysis was performed using a t test, *P < 0.05, **P < 0.01, and ***P < 0.001.) (D) Representative results of expressions of M1 and M2 polarization markers in MDMs detected by flow cytometry. (Statistical analysis was performed using a t test, *P < 0.05).