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. 2023 Oct 5;6(12):e202302148. doi: 10.26508/lsa.202302148

Figure S2. Heptelidic acid inhibits glycolysis and inflammation induced by HIV-1 infection, whereas oligomycin exerts the opposite effect.

Figure S2.

Monocyte-derived macrophages were treated with 10 μM heptelidic acid (HA) or 40 μM oligomycin (Omy) for 8 h during the 48 h of HIV-1 infection. (A, B, C, D) Lactate concentration in the culture supernatant (A), and expressions of TNF-α, IL-1β, and IL-6 (B, C, D) were detected. (Statistical analysis was performed using a t test, *P < 0.05, **P < 0.01, and ***P < 0.001 as compared to Control; #P < 0.05, ##P < 0.01, and ###P < 0.001 as compared to HIV-1).