Table 2.

Flow correlation

Marker	r	P
Flow correlation at rest
pAKT	0.71	.09
AKT	0.12	.84
p/AKT ratio	0.86	.02
pBAD	−0.86	.02
pBCL-2	−0.43	.35
BCL-2	−0.50	.27
p/BCL-2 ratio	0.14	.78
ERK	0.25	.59
pFOXO1	−0.61	.17
FOXO1	−0.61	.17
p/FOXO1 ratio	0.50	.27
PI3K	−0.61	.17
Flow correlation with pacing
pAKT	−0.61	.17
AKT	−0.50	.27
p/AKT ratio	−0.29	.56
pBAD	0.21	.66
pBCL-2	0.29	.56
BCL-2	0.07	.91
p/BCL-2 ratio	0.11	.84
ERK	0.11	.84
pFOXO1	0.21	.66
FOXO1	0.11	.84
p/FOXO1 ratio	−0.07	.91
PI3K	−0.25	.59

Shown is the correlation of blood flow to the ischemic myocardium at rest and while pacing at 150 beats per minute from our prior study to the expression of significant apoptotic markers in the hypoxia-conditioned extracellular vesicle group (n = 7).¹⁰ Table shows correlation coefficient (r) and P-values calculated using the Spearman rank correlation coefficient. P values less than .05 are shown in bold. pAKT, Phospho-protein kinase B; AKT, protein kinase B; pBAD, phospho-Bcl-2-associated death promoter; pBcl-2, phospho-B-cell lymphoma 2; Bcl-2, B-cell lymphoma 2; ERK, extracellular signal-regulated kinase; pFOXO1, phospho-forkhead box O; FOXO1, forkhead box O1; PI3K, phosphoinositide 3-kinase.