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. 2023 Jul 6;15:242–251. doi: 10.1016/j.xjon.2023.06.014

Figure 2.

Figure 2

Coronary endothelial responses of mouse microvessels to endothelium-dependent vasodilator NS309. A, Dose-dependent vasodilation of sham control mouse microvessels and vessels undergoing CP-H/R with or without RBX treatment in response to the SK channel activator NS309 (10–9-10–5 M). B, Bar graph shows vasodilation response to NS309 10–5 M. CP-H/R, Microvessels undergoing hypoxia/reoxygenation; RBX + CP-H/R, microvessels pretreated with RBX before hypoxia and reoxygenation; RBX, ruboxistaurin.