Table 2.

Univariate and multivariate analyses of Prognostic factor for overall survival

	Univariate analysis		Multivariate analysis
Variables	HR (95% CI)	P*	HR (95% CI)	P*
Age	1.022 (1.000-1.044)	0.048	1.008 (0.984–1.033)	0.516
Sex
Male	1
Female	0.916 (0.567–1.479)	0.720
BMI	0.971 (0.890–1.058)	0.499
ASA class
1/2	1		1
3/4	1.810 (1.115–2.938)	0.016	1.713 (0.950–3.092)	0.074
Location
Right colon	1
Left colon	0.756 (0.429–1.332)	0.333
Rectum	0.852 (0.467–1.556)	0.602
Size
d<5	1
d ≥ 5	0.986 (0.610–1.592)	0.954
Differentiation
Low	1
Medium	0.838 (0.410–1.716)	0.630
High	1.000 (0.427–2.342)	0.999
TNM stage
TNM I/II	1		1
TNM III/IV	2.093 (1.255–3.490)	0.005	4.320 (1.446–12.903)	0.009
Tumor
T1/2	1
T3/4	1.980 (0.856–4.582)	0.110
Node
N0	1		1
N1/2	1.753 (1.071–2.868)	0.026	0.488 (0.169–1.408)	0.185
Metastasis
0	1
1	1.882 (0.591–5.992)	0.285
Vascular Tumor Thrombus
No	1
Yes	1.503 (0.875–2.582)	0.140
Nerve Invasion
No	1		1
Yes	1.856 (1.126–3.059)	0.015	1.890 (1.124–3.178)	0.016
LNR (%)	2.096 (0.680–6.464)	0.198
SEMS implantation
No	1
Yes	1.230 (0.681–2.222)	0.492
Chemotherapy
No	1
Yes	0.961 (0.591–1.562)	0.872
Radiotherapy
No	1
Yes	0.519 (0.072–3.742)	0.515
CEA	1.000 (1.000–1.000)	0.132
M-NPS Group
0	1		1
1	2.730 (1.398–5.332)	0.003	2.635 (1.330–5.221)	0.006
2	4.893 (2.259–10.601)	< 0.001	4.930 (2.217–10.964)	< 0.001

* (OS) Multivariate analysis adjusted for age, ASA class, TNM stage, node and nerve Invasion. We use a stepwise regression approach for multivariate analysis