Table 3.
Univariate and multivariate analyses of prognostic factor for disease-free survival
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| Variables | HR (95% CI) | P* | HR (95% CI) | P* |
| Age | 1.012 (0.992–1.032) | 0.236 | ||
| Sex | ||||
| Male | 1 | |||
| Female | 1.145 (0.721–1.820) | 0.565 | ||
| BMI | 1.021 (0.938–1.110) | 0.636 | ||
| ASA class | ||||
| 1/2 | 1 | 1 | ||
| 3/4 | 1.742 (1.092–2.780) | 0.020 | 1.763 (1.090–2.851) | 0.021 |
| Location | ||||
| Right colon | 1 | |||
| Left colon | 0.768 (0.446–1.323) | 0.341 | ||
| Rectum | 0.859 (0.480–1.539) | 0.610 | ||
| Size | ||||
| d<5 | 1 | |||
| d ≥ 5 | 0.923 (0.581–1.465) | 0.733 | ||
| Differentiation | ||||
| Low | 1 | |||
| Medium | 0.983 (0.483–2.001) | 0.961 | ||
| High | 1.256 (0.543–2.905) | 0.594 | ||
| TNM stage | ||||
| TNM I/II | 1 | 1 | ||
| TNM III/IV | 1.655 (1.029–2.664) | 0.038 | 1.902 (1.165–3.104) | 0.010 |
| Tumor | ||||
| T1/2 | 1 | |||
| T3/4 | 1.633 (0.783–3.407) | 0.191 | ||
| Node | ||||
| N0 | 1 | |||
| N1/2 | 1.298 (0.815–2.066) | 0.272 | ||
| Metastasis | ||||
| 0 | 1 | |||
| 1 | 1.851 (0.582–5.886) | 0.297 | ||
| Vascular Tumor Thrombus | ||||
| No | 1 | |||
| Yes | 1.243 (0.721–2.145) | 0.434 | ||
| Nerve Invasion | ||||
| No | 1 | |||
| Yes | 1.573 (0.964–2.567) | 0.070 | ||
| LNR (%) | 1.360 (0.422–4.388) | 0.607 | ||
| SEMS implantation | ||||
| No | 1 | |||
| Yes | 1.163 (0.657–2.057) | 0.604 | ||
| Chemotherapy | ||||
| No | 1 | |||
| Yes | 0.937 (0.586–1.496) | 0.784 | ||
| Radiotherapy | ||||
| No | 1 | |||
| Yes | 1.133 (0.278–4.624) | 0.862 | ||
| CEA | 1.000 (1.000–1.000) | 0.193 | ||
| M-NPS Group | ||||
| 0 | 1 | 1 | ||
| 1 | 2.128 (1.160–3.905) | 0.015 | 2.031 (1.104–3.737) | 0.023 |
| 2 | 3.691 (1.791–7.608) | < 0.001 | 3.508 (1.691–7.277) | < 0.001 |
* (DFS) Multivariate analysis adjusted for ASA class and TNM stage