Table 2.
Baseline differences in patients initiated on parenteral prostacyclin versus non-parenteral prostacyclin.
| Baseline variables | Non-parenteral therapy [mean ± SD/median (IQR) or frequency/%] | Parenteral therapy [mean ± SD/median (IQR) or frequency/%] | p Value |
|---|---|---|---|
| Syncope or pre-syncope | 5 (11.9%) | 6 (46.2%) | 0.039 |
| Body mass index (kg/m2) | 27.9 (23.3, 31.1) | 23.2 (21.9, 26.3) | 0.004 |
| WHO functional class IV | 0 (0%) | 3 (23.1%) | 0.006 |
| Number of hospitalization | 0.46 ± 0.72 | 1.81 ± 1.56 | <0.001 |
| Right ventricle function (hypokinetic) | 25 (59.5%) | 10 (83.3%) | 0.039 |
| Tricuspid annulus planar systolic excursion (low) | 15 (42.9%) | 9 (81.8%) | 0.019 |
| Systolic pulmonary artery pressure (mm Hg) | 75 ± 18 | 90 ± 17 | 0.005 |
| Diastolic pulmonary artery pressure (mm Hg) | 29 ± 8 | 35 ± 8 | 0.045 |
| Mean pulmonary artery pressure (mm Hg) | 45 ± 12 | 53 ± 10 | 0.033 |
| Pulmonary vascular resistance (woods units) | 7.6 (5.5, 10.4) | 12.0 (7.6, 15.9) | 0.085 |
IQR, interquartile range.