. Author manuscript; available in PMC: 2024 Oct 2.

Published in final edited form as: Behav Brain Res. 2023 Aug 18;454:114632. doi: 10.1016/j.bbr.2023.114632

Table 3b:

ALE Cluster Results (Negative Stimuli, MDD < HC Group Contrast)

Cluster Location	Cluster Size (mm³)	Coordinates (Center)			Coordinates (Peak)			Peak Z- score	ALE Score (10⁻²)	Contributing Studies
		x	y	z	x	y	z
Left Medial Frontal Gyrus (MFG)	4424	−4	37.5	31.1	−2	38	34	4.60	0.98	1 foci	Greening et al., 2013 Facial emotion recognition, Neutral Face with Negative Distractor, MDD < HC
Left Medial Frontal Gyrus (MFG)	4424	−4	37.5	31.1	−2	38	34	4.60	0.98	1 foci	Laurent & Albow, 2013 Distressed Faces, Own vs. Other Infant, MDD < HC
Left Inferior Frontal Gyrus (IFG)	4120	−42.9	42.8	−9.6	−44	42	−10	4.78	1.12	1 foci	Greening et al., 2013 Facial emotion recognition, Neutral Face with Negative Distractor, MDD < HC
Left Inferior Frontal Gyrus (IFG)	4120	−42.9	42.8	−9.6	−44	42	−10	4.78	1.12	1 foci	*Keedwell et al., 2013* Negative mood induction with sad faces; MDD < HC

Note: ALE = Activation Likelihood Estimate; HC = healthy control; MDD = Major Depressive Disorder All coordinates in Montreal Neurological Institute (MNI) space; ALE cluster derived from cluster-forming p < 0.01 and family wise-error (FWE) cluster threshold p < 0.05; Number of permutations = 5000