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An outline of the framework for evaluation of perturbation-bases massively parallel assays technique. In the “Three sequence designing approaches” box, we used the “GATA_known9” motif as an example. In detail, the GATA motifs are a group of sequences conforming to the consensus WGATAR (W = A or T and R = A or G) (marked by the wavy underline), that can be recognized and bound by GATAbinding transcription factors (35).
