TABLE 2.
Annual percentage changes in cancer death rates by rural–urban status and cancer site among males aged ≥25 years in the United States, 1999–2020.
| Cause of Death | AAPC | Segment 1 | Segment 2 | Segment 3 | |||
|---|---|---|---|---|---|---|---|
| Urban | |||||||
| All malignant cancers | −1.96 (−2.03, −1.90) | 1999–2014 | −1.86 (−1.91, −1.81) | 2014–2020 | −2.23 (−2.43, −2.03) | N/A | N/A |
| Colon and rectum | −2.82 (−3.00, −2.64) | 1999–2011 | −3.31 (−3.54, −3.08) | 2011–2020 | −2.16 (−2.50, −1.53) | N/A | N/A |
| Kidney and renal pelvis | −1.14 (−1.49, −0.79) | 1999–2014 | −0.74 (−0.99, −0.48) | 2014–2020 | −2.15 (−3.28, −1.00) | N/A | N/A |
| Leukemia | −1.44 (−1.62, −1.27) | 1999–2012 | −0.85 (−1.07, −0.64) | 2012–2020 | −2.39 (−2.75, −2.04) | N/A | N/A |
| Liver and intrahepatic bile | 1.74 (1.57, 1.92) | 1999–2013 | 2.74 (2.56, 2.93) | 2013–2020 | −0.23 (−0.65, 0.19) | N/A | N/A |
| Lung and bronchus | −3.49 (−3.62, −3.35) | 1999–2005 | −2.02 (−2.31, −1.73) | 2005–2013 | −3.14 (−3.38, −2.90) | 2013–2020 | −5.11 (−5.35, −4.88) |
| Myeloma | −1.10 (−1.41, −0.78) | 1999–2016 | −0.85 (−1.02, −0.69) | 2016–2020 | −2.11 (−3.75, −0.45) | N/A | N/A |
| Non‐Hodgkin lymphoma | −2.58 (−2.75, −2.41) | 1999–2006 | −3.28 (−3.74, −2.82) | 2006–2020 | −2.23 (−2.38, −2.08) | N/A | N/A |
| Pancreas | 0.13 (0.06, 0.20) | 1999–2020 | 0.13 (0.06, 0.20) | N/A | N/A | N/A | N/A |
| Prostate | −2.48 (−2.68, −2.27) | 1999–2013 | −3.39 (−3.57, −3.21) | 2013–2020 | −0.62 (−1.19, −0.05) | N/A | N/A |
| Stomach | −2.92 (−3.05, −2.78) | 1999–2006 | −3.57 (−3.87, −3.27) | 2006–2020 | −2.59 (−2.74, −2.44) | N/A | N/A |
| Urinary bladder | −0.61 (−0.83, −0.39) | 1999–2014 | −0.07 (−0.24, 0.11) | 2014–2020 | −1.94 (−2.63, −1.24) | N/A | N/A |
| Rural | |||||||
| All malignant cancers | −1.43 (−1.47, −1.39) | 1999–2020 | −1.43 (−1.47, −1.39) | N/A | N/A | N/A | N/A |
| Colon and rectum | −2.01 (−2.20, −1.83) | 1999–2009 | −2.66 (−2.95, −2.36) | 2009–2020 | −1.43 (−1.70, −1.15) | N/A | N/A |
| Kidney and renal pelvis | −0.33 (−0.51, −0.14) | 1999–2020 | −0.33 (−0.51, −0.14) | N/A | N/A | N/A | N/A |
| Leukemia | −1.12 (−1.29, −0.95) | 1999–2020 | −1.12 (−1.29, −0.95) | N/A | N/A | N/A | N/A |
| Liver and intrahepatic bile | 2.41 (1.59, 3.25) | 1999–2007 | 1.87 (0.66, 3.10) | 2007–2012 | 5.05 (2.06, 8.12) | 2012–2020 | 1.34 (0.49, 2.20) |
| Lung and bronchus | −2.70 (−2.98, −2.43) | 1999–2007 | −1.47 (−1.86, −1.08) | 2007–2014 | −2.56 (−3.14, −1.97) | 2014–2020 | −4.49 (−5.08, −3.90) |
| Myeloma | −0.91 (−1.14, −0.68) | 1999–2020 | −0.91 (−1.14, −0.68) | N/A | N/A | N/A | N/A |
| Non‐Hodgkin lymphoma | −2.13 (−2.30, −1.95) | 1999–2020 | −2.13 (−2.30, −1.95) | N/A | N/A | N/A | N/A |
| Pancreas | 0.66 (0.52, 0.81) | 1999–2020 | 0.66 (0.52, 0.81) | N/A | N/A | N/A | N/A |
| Prostate | −2.54 (−2.78, −2.30) | 1999–2014 | −3.49 (−3.68, −3.31) | 2014–2020 | −0.11 (−0.90, 0.69) | N/A | N/A |
| Stomach | −2.75 (−3.20, −2.30) | 1999–2007 | −3.75 (−4.68, −2.81) | 2007–2020 | −2.13 (−2.66, −1.60) | N/A | N/A |
| Urinary bladder | 0.08 (−0.24, 0.41) | 1999–2010 | 0.77 (0.26, 1.27) | 2010–2020 | −0.66 (−1.15, −0.18) | N/A | N/A |
Segments were chosen by Joinpoint regression. Boldfaced cell indicates statistical significance (p < 0.05).
Abbreviations: AAPC, average annual percentage change; APC, annual percentage change; N/A, not applicable.