TABLE 2.
Univariate analysis of OS and PFS of bulky mass DLBCL.
| Variables | OS | PFS | ||
|---|---|---|---|---|
| HR (95% CI) | p Value | HR (95% CI) | p Value | |
| Male (vs. female) | 1.047 (0.693 ~ 1.580) | 0.828 | 1.123 (0.788 ~ 1.600) | 0.522 |
| Age ≥60 years | 2.822 (1.871 ~ 4.257) | <0.001 | 2.106 (1.489 ~ 2.978) | <0.001 |
| Ann Arbor Stage 3–4 | 3.046 (1.692 ~ 5.483) | <0.001 | 2.893 (1.793 ~ 4.669) | <0.001 |
| IPI 3–5 | 4.377 (2.636 ~ 7.270) | <0.001 | 2.850 (1.938 ~ 4.191) | <0.001 |
| GCB (vs. non‐GCB) | 1.275 (0.825 ~ 1.970) | 0.274 | 1.203 (0.825 ~ 1.753) | 0.337 |
| LDH elevated | 1.399 (0.725 ~ 2.700) | 0.317 | 1.652 (0.930 ~ 2.935) | 0.087 |
| β2‐MG elevated | 2.299 (1.513 ~ 3.492) | <0.001 | 2.169 (1.524 ~ 3.087) | <0.001 |
| MTD ≥10 cm | 1.246 (0.829 ~ 1.871) | 0.290 | 1.372 (0.969 ~ 1.942) | 0.074 |
| Comorbidity | 1.917 (1.266 ~ 2.904) | 0.002 | 1.479 (1.027 ~ 2.129) | 0.035 |
| MYC/BCL2 DE | 1.292 (0.848 ~ 1.969) | 0.232 | 1.349 (0.922 ~ 1.972) | 0.124 |
| MYC overexpression | 1.687 (1.079 ~ 2.637) | 0.022 | 1.824 (1.249 ~ 2.664) | 0.002 |
Abbreviations: CI, confidence interval; DE, double expression; HR, hazard ratio.