Table 2:

Outcome metrics comparing the exAPD algorithm versus the exMPC algorithm during the primary in-clinic session

	exAPD	exMPC	Difference	p value (exAPD vs exMPC)	p value (sequence)	p value (period)
% time below range (<3·9 mmol/L)*	2·5 (7·0)	1·3 (2·9)	−1·2 (7·3)	0·46	0·50	0·22
% time in range (3·9–10·0 mmol/L)	59·4 (23·1)	63·2 (23·9)	3·8 (29·8)	0·49	0·41	0·047
% high glucose (>10 mmol/L)	38·1 (21·4)	35·5 (24·4)	−2·6 (28·4)	0·63	0·34	0·012
% very low glucose (<3·0 mmol/L)	0·27 (0·87)	0	··	··	··	··
% very high glucose (>13·9 mmol/L)	8·0 (15·8)	7·5 (11·4)	−0·5 (16·0)	0·87	0·65	0·24
Mean glucose (mmol/L)	9·4 (1·6)	9·2 (1·6)	−0·2 (1·8)	0·63	0·59	0·15
Rescue carbohydrate (count)†	1·09 (2·16)	0·58 (0·93)	−0·51 (2·36)	0·33	0·31	0·33
Insulin (units)‡	21·2 (8·0)	21·4 (10·0)	0·3 (4·7)	0·94	0·60	0·60

Data are mean (SD) or difference (SD). The p value for sequence indicates the significance of the sequence of doing the exAPD verus exMPC first. The p value for the period indicates whether the order of doing the intervention, regardless of the type, was significant. exAPD=exercise-aware adaptive proportional derivative. exMPC=exercise-aware model predictive control.

^*p values estimated using bootstrapped standard errors.

^†p values from negative binomial (count) regression model.

^‡p values from mixed effects regression model on insulin units.