Comparison 1. Pars plana vitrectomy (PPV) with internal limiting membrane (ILM) inverted flap versus PPV with ILM peeling.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Mean logMAR best‐corrected visual acuity (one month)	4	254	Mean Difference (IV, Random, 95% CI)	‐0.08 [‐0.20, 0.05]
1.2 Mean logMAR best‐corrected visual acuity (three months or more)	4	276	Mean Difference (IV, Random, 95% CI)	‐0.17 [‐0.23, ‐0.10]
1.2.1 Three months	2	115	Mean Difference (IV, Random, 95% CI)	‐0.17 [‐0.26, ‐0.07]
1.2.2 Six months	1	60	Mean Difference (IV, Random, 95% CI)	‐0.12 [‐0.23, ‐0.01]
1.2.3 One year	1	101	Mean Difference (IV, Random, 95% CI)	‐0.22 [‐0.35, ‐0.09]
1.3 Proportion of eyes achieving closure of macular hole	4	276	Risk Ratio (M‐H, Random, 95% CI)	1.10 [1.02, 1.18]
1.4 Proportion of eyes achieving type 1 macular hole closure	4		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.4.1 Type 1	4	276	Risk Ratio (M‐H, Random, 95% CI)	1.31 [1.03, 1.66]