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. 2023 Oct 2;18:2163–2177. doi: 10.2147/COPD.S419634

Table 6.

The Top 10 Cited Articles

Rank Title Year Citations Journal IF (2021)
1 Transcriptome-based network analysis reveals a spectrum model of human macrophage activation 2014 1079 Immunity 43.47
2 Muc5b is required for airway defence 2014 406 Nature 69.50
3 Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model 2015 232 Plos One 3.75
4 Randomised, double-blind, placebo-controlled trial with azithromycin selects for anti-inflammatory microbial metabolites in the emphysematous lung 2016 228 Thorax 9.1
5 Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model 2011 206 Sci Transl Med 19.32
6 Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers 2012 182 Am J Med Genet B Neuropsychiatr Genet 3.36
7 Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection 2015 174 Immunity 43.47
8 IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke 2011 156 Plos One 3.75
9 A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis 2013 148 J Allergy Clin Immunol 14.29
10 Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress 2011 130 Biochem Biophys Res Commun 3.32

Abbreviation: IF, impact factor.