Figure 1.

Deletion of adipocyte GR did not affect the body weight, adiposity, or adipocyte size. (A), (D) Body weight of male (solid bars) and female (striped bars) GR Flox and Adipo GRKO mice (n = 7 mice/genotype). (B), (E) Ratio of different adipose tissue depot weight to body weight was calculated as a measure of adiposity in GR Flox and Adipo GRKO male and female mice (n = 4-6 mice/genotype). (C), (F) Representative hematoxylin and eosin stained image of GR Flox and Adipo GRKO male and female mesenteric adipose tissue. Average adipocyte area was calculated using ImageJ software (n = 3 mice/genotype). Scale bar: 10 μm. All values represent mean ± SD. Data were statistically analyzed using unpaired Student's t-test.

Abbreviations: Adipo GRKO, adipocyte-specific GR knockout; GR, glucocorticoid receptors; GR Flox, C57BL/6J GR flox/flox; GRKO, GR knockout.