Table 4. The effect of SPI, MNPs and nZVI on the level of ALT, AST, urea and creatinine in sera of mice of non infected treated subgroups compared to their non treated control.
| Subgroup Biomarker |
Non treated (Ia) | SPI-treated (Ib) | MNPs-treated (Ic) | nZVI-treated (Id) | F | p |
|---|---|---|---|---|---|---|
| ALT (IU/L) | ||||||
| Median (Min.–Max.) | 26.5 (25–28) | 26.2 (24.3–29) | 26.8 (24.7–28.5) | 27.3 (26.1–30) | 0.705 | 0.560 |
| Mean ± SD | 26.54 ± 1.29 | 26.44 ± 1.58 | 26.71 ± 1.53 | 27.53 ± 1.39 | ||
| AST (IU/L) | ||||||
| Median (Min.–Max.) | 22.9 (21–25.8) | 23.8 (22.3–26.5) | 24.3 (20.7–25.6) | 24.1 (22.16–27.0) | 0.459 | 0.714 |
| Mean ± SD | 23.13 ± 1.84 | 24.10 ± 1.84 | 23.76 ± 1.81 | 24.28 ± 1.81 | ||
| Urea (mg/dl) | ||||||
| Median (Min.–Max.) | 14 (10.7–16) | 15.5 (11.5–16.5) | 13.2 (11–15.7) | 14.2 (12.9–17.1) | 0.847 | 0.484 |
| Mean ± SD | 13.9 ± 2 | 14.8 ± 2 | 13.3 ± 1.6 | 14.7 ± 1.9 | ||
| Creatinine (mg/dl) | ||||||
| Median (Min.–Max.) | 0.70 (0.54–0.88) | 0.73 (0.65–0.90) | 0.79 (0.57–0.92) | 0.70 (0.65–0.95) | 0.387 | 0.763 |
| Mean ± SD | 0.70 ± 0.13 | 0.75 ± 0.09 | 0.77 ± 0.13 | 0.75 ± 0.12 |
F: F for One way ANOVA test, used in comparison between more than two groups
p: p value for comparing between the subgroups