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. 2023 Oct 4;52(5):111. doi: 10.3892/ijmm.2023.5314

Figure 5.

Figure 5

Targeting inflammatory signaling pathways with drugs shows promise in AD treatment. By modulating various signaling pathways, drugs and inhibitors can effectively target microglia, neurons, and mice with AD. This targeted approach helps regulate inflammatory responses, promote neuronal survival, and restore functional recovery, ultimately alleviating symptoms of AD. AD, Alzheimer's disease; NLRP3, NOD-like receptor thermal protein domain associated protein 3; CREB, cyclic AMP response element binding; PPAR, Peroxisome proliferator-activated receptor; Nrf2, Nuclear factor erythroid 2-related factor 2.