TABLE 2.

Therapeutic efficacy of topically applied NND-502, lanoconazole, and terbinafine in the guinea pig model of tinea pedis (first experiment)^d

Treatment	No. of culture-positive feet/total no. of feet (%)	Average intensity of infection score
3-Day
Untreated control	10/10 (100)	5.8
PEG400a	10/10 (100)	5.6
0.5% NND-502	3/10 (30)b,c	0.25b,c
0.5% Lanoconazole	7/10 (70)	0.8b,c
0.5% Terbinafine	5/10 (50)b,c	0.7b,c
7-Day
Untreated control	10/10 (100)	6.1
PEG400	10/10 (100)	5.7
0.5% NND-502	0/10 (0)b,c	0b,c
0.5% Lanoconazole	2/10 (20)b,c	0.1b,c
0.5% Terbinafine	1/10 (10)b,c	0.1b,c

^aPolyethylene glycol 400. 

^bSignificantly different (P < 0.05) from values obtained for the comparable untreated control group. 

^cSignificantly different from values obtained for the comparable PEG400 group. 

^dNo significant differences were found in any of the parameters among the comparable 0.5% NND-502, 0.5% lanoconazole, and 0.5% terbinafine groups.