Table 1.
The basic characteristics of all the included studies.
| Study ID | Country | HT/C (N) | Age of Patients HT/C(years) | Inclusion criteria |
sampling time of blood | Assay method | sensitivity of assay(ng/ml) | AMH HT/C (ng/mL) |
NOS Scores |
|
|---|---|---|---|---|---|---|---|---|---|---|
| HT | C | |||||||||
| Shou 2021 |
China | 63/48/45/53 | 29.71 ± 4.14/28.73 ± 3.62/28.62 ± 4.11/29.45 ± 3.84 | 3 groups: euthyroid; subclinical hypothyroidism; overt hypothyroidism |
healthy fertile women | in the early follicular phase (days 2–4) | ECLIA | – | 2.86 ± 1.05/2.40 ± 1.02/1.31 ± 1.27/3.01 ± 0.78 | 7 |
| Shou (1) 2021 |
China | 86/34/29/45 | 30.6(R:18–40)/— | 3 groups from rural women: euthyroid; subclinical hypothyroidism; overthypothyroidism |
healthy rural fertile women | – | ECLIA | – | 2.81 ± 1.02/2.21 ± 1.04/1.29 ± 1.21/2.79 ± 1.01 | 6 |
| Tuten 2014 |
Turkey | 32/49 | 34.93 ± 8.87/34.16 ± 4.74 | premenopausal women with HT under replacement therapy with thyroxine | healty women | in the early follicular phase | ELISA | 0.006 | 4.54 ± 4.59/2.45 ± 1.27 | 8 |
| Pirgon 2015 |
Turkey | 30/30 | 15.1 ± 1.4/15.2 ± 1.4 | non-obese HT, adolescents, euthyroid | healthy adolescents | in the early follicular phase | ELISA | 0.09 | 10.6 ± 10.4/7.5 ± 7.3 | 9 |
| Ünsal 2021 |
Turkey | 108/172 | 32(IQR:27.3–38)/31 (25–37) | euthyroid HT | healthy women | in the early follicular phase |
ECLIA | – | 1.99 ± 2.13/2.41 ± 2.02 | 7 |
| Akin 2018 |
Turkey | 30/30 | 14.4 ± 1.85/14.4 ± 1.85 | adolescent HT, either euthyroid or subclinical hypothyroidism | euthyroid and auto-antibody negative adolescents | – | ELISA | 0.08 | 1.96 ± 1.13/2.06 ± 1.28 | 8 |
| Felipe 2021 |
Mexico | 27/25 | 27.70 ± 4.71/26.2 ± 3.02 | primary HT | normal levels of thyroid hormones and negative for anti-TPO antibodies |
– | ELISA | 0.35 | 2.42 ± 1.86/2.77 ± 2.50 | 8 |
| Kucukler 2018 |
Turkey | 21/21/32 | 35.4 ± 5.9/34.2 ± 4.7/32.0 ± 5.1 | subclinical HT; overt HT |
healthy women | in the early follicular phase (days 2–4) | ECLIA | – | 1.5 ± 1.3/1.8 ± 2.2/2.1 ± 1.4 | 8 |
| Erol 2016 |
Turkey | 57/50 | 15.4 ± 1.4/15.1 ± 1.6 | euthyroid adolescent HT | healthy adolescents | in the early follicular phase (days 3–5) | ELISA | 0.028 | 4.68 ± 1.61/2.73 ± 1.25 | 8 |
| Adamska 2021 |
Poland | 39/46 | 26.8(IQR:24–29)/26 (25–27) | euthyroid HT | healthy women | in the early follicular phase (days 3–5) | ELISA | 0.08 | 5.09 ± 3.46/6.48 ± 3.14 | 8 |
Notes: ‘—’: No report, HT: Hashimoto's thyroiditis, C:control group, AMH: anti-Müllerian hormone, R: range from minimum to maximum, IQR: interquartile range, ECLIA: electrochemiluminescence immunoassay, ELISA: enzyme-linked immunosorbent assay.