Table 1.

Sensitivity (Sn) and specificity (Sp) for major osteoporotic (a) and hip (b) fractures by considering the FRAX tool (with or without BMD) and different cut-off (3%, 5%, 10%, 20%, 30%)

(a) Major osteoporotic fractures
Cut-off	3%		5%		10%		20%		30%
FRAX	With BMD (95% CI)	without BMD (95% CI)	With BMD (95% CI)	Without BMD (95% CI)	With BMD (95% CI)	Without BMD (95% CI)	With BMD (95% CI)	Without BMD (95% CI)	With BMD (95% CI)	Without BMD (95% CI)
Women
Sn	67 [30–93]	57–85 [49–90]	66 [57–73]	34 [27–42]	42–97 [28–98]	46–100 [31–100]	8–41 [2–44]	8 [2–20]	–	4 [0–14]
Sp	75 [63–84]	34–79 [23–82]	71 [67–74]	89 [86–91]	15–84 [14–88]	0–77 [0–81]	81–97 [80–98]	95 [93–97]	99 [97–100]	99 [98–100]
Total
Sn	–	52–85 [42–90]	–	34–35 [26–44]	42–97 [28–98]	24–100 [16–100]	8–41 [2–44]	8–29 [2–31]	0–9 [0–11]	4–10 [0–14]
Sp		34–79 [23–82]		81–89 [71–91]	15–84 [14–88]	0–93 [0–97]	81–97 [80–98]	88–95 [87–97]	98–99 [97–100]	97–99 [97–100]

(b) Hip fractures
cut-off	3%		5%		10%
FRAX	With BMD (95% CI)	Without BMD (95% CI)	With BMD (95% CI)	Without BMD (95% CI)	With BMD (95% CI)
Women
Sn	43–62 [28–64]	8–77 [0–82]	29–76 [19–80]	42–78 [41–82]	33 [28–39]
Sp	72–87 [69–89]	39–100 [36–100]	63–91 [61–94]	50–92 [49–92]	86 [85–87]
Total
Sn	43–77 [28–81]	8–78 [0–82]	29–76 [19–80]	22–78 [14–82]	–
Sp	72–87 [69–89]	39–100 [36–100]	63–91 [61–94]	50–97 [49–99]

We reported the minimum and the maximum Sn/Se value, the lower and the upper limit of the 95% confidence interval (CI)