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. 2023 Oct 6;13:16855. doi: 10.1038/s41598-023-44183-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Synapse gene module deconvolution. (A) Heatmap showing the synapse module genes in the five cell types. (B) Correlation network of NEU genes. (C) Dot plot showing gene fold changes of old versus young animals from our deconvoluted data, Ximerakis et al.¹², Allen et al.¹³ and Lee et al.¹⁴. NEU genes are denoted in purple, and VC genes in green.