Table 1.
Clinicopathological characteristics of HCC patients from TCGA.
| Training dataset (n = 127) | Validation dataset (n = 124) | P-value | Total (n = 251) | |
|---|---|---|---|---|
| Age (years) | 0.944 | |||
| ≤ 60 | 62 (48.8%) | 59 (47.6%) | 121 (48.2%) | |
| >60 | 65 (51.2%) | 65 (52.4%) | 130 (51.8%) | |
| Gender | 0.0279 | |||
| female | 29 (22.8%) | 45 (36.3%) | 74 (29.5%) | |
| male | 98 (77.2%) | 79 (63.7%) | 177 (70.5%) | |
| Alpha-fetoprotein (ng/ml) | 0.749 | |||
| ≤ 20 | 62 (48.8%) | 57 (46.0%) | 119 (47.4%) | |
| >20 | 45 (35.4%) | 47 (37.9%) | 92 (36.7%) | |
| Missing | 20 (15.7%) | 20 (16.1%) | 40 (15.9%) | |
| Liver cirrhosis | 0.804 | |||
| No | 52 (40.9%) | 47 (37.9%) | 99 (39.4%) | |
| Yes | 30 (23.6%) | 31 (25.0%) | 61 (24.3%) | |
| Missing | 45 (35.4%) | 46 (37.1%) | 91 (36.3%) | |
| Etiology | 0.999 | |||
| Alcohol consumption | 17 (13.4%) | 17 (13.7%) | 34 (13.5%) | |
| Hepatitis B | 42 (33.1%) | 42 (33.9%) | 84 (33.5%) | |
| Hepatitis C | 20 (15.7%) | 19 (15.3%) | 39 (15.5%) | |
| Other factors | 40 (31.5%) | 39 (31.5%) | 79 (31.5%) | |
| Missing | 8 (6.3%) | 7 (5.6%) | 15 (6.0%) | |
| Race | 0.223 | |||
| Asian | 55 (43.3%) | 60 (48.4%) | 115 (45.8%) | |
| Others | 4 (3.1%) | 9 (7.3%) | 13 (5.2%) | |
| White | 63 (49.6%) | 53 (42.7%) | 116 (46.2%) | |
| Missing | 5 (3.9%) | 2 (1.6%) | 7 (2.8%) | |
| Histological grade | 0.0482 | |||
| G1-G2 | 86 (67.7%) | 68 (54.8%) | 154 (61.4%) | |
| G3-G4 | 40 (31.5%) | 55 (44.4%) | 95 (37.8%) | |
| Missing | 1 (0.8%) | 1 (0.8%) | 2 (0.8%) | |
| TNM stage | 0.347 | |||
| I | 90 (70.9%) | 80 (64.5%) | 170 (67.7%) | |
| II | 37 (29.1%) | 44 (35.5%) | 81 (32.3%) | |
| Event | 0.425 | |||
| Yes | 46 (36.2%) | 52 (41.9%) | 98 (39.0%) | |
| No | 81 (63.8%) | 72 (58.1%) | 153 (61.0%) |