Fig. 3.

Relative gene expression [mean fold change] of (a) JAK1, (b) JAK2, (c) JAK3, and (d) TYK2 in the different groups of treatments. Data were normalized with gapdh. Data were represented as mean SD. The number 24 and 48 refers to different time orders of HT-29 cell line treatments. C, control; SP, Sonicated Pathogen; P + L, sonicated pathogen, and Lactobacillus spp. were added simultaneously.; P + B, sonicated pathogen, and Bifidobacterium spp. were added simultaneously; P + LB, sonicated pathogen, and Lac/Bif were added simultaneously. Data were considered as statistically significant when p < 0.05 (*p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001).