TABLE 1.

In vitro activities of ketoconazole, itraconazole, and fluconazole against B. dermatitidis isolates^a

Isolate	Ketoconazole				Itraconazole				Fluconazole
	MIC		MLC		MIC		MLC		MIC		MLC
	T1	T2	T1	T2	T1	T2	T1	T2	T1	T2	T1	T2
1	0.4	0.8	0.8	1.6	≤0.018	0.07	0.07	0.15	20	40	40	80
2	0.4	0.4	0.4	1.6	≤0.018	≤0.018	0.035	0.30	5	20	20	40
3	0.2	0.2	0.4	0.8	0.035	0.035	0.035	0.035	10	20	20	20
4	0.1	0.4	0.4	0.8	≤0.018	0.035	0.035	0.035	2.5	20	20	40
5b	0.2	0.2	0.8	0.8	≤0.018	≤0.018	≤0.018	0.035	40	80	80	>80
6	0.1	0.4	0.4	1.6	≤0.018	0.035	0.035	0.035	2.5	20	20	20
7	0.4	0.4	0.4	3.2	≤0.018	0.035	0.035	0.035	10	40	40	40
8	0.2	0.2	0.2	3.2	≤0.018	≤0.018	≤0.018	≤0.018	10	20	20	80
9	0.2	0.2	0.2	6.4	≤0.018	0.035	0.035	0.15	40	40	40	>80
10	0.2	0.2	0.2	1.6	≤0.018	≤0.018	≤0.018	≤0.018	5	10	10	40
11	0.4	0.4	0.4	6.4	≤0.018	0.035	0.07	0.15	20	40	40	>80
12b	0.2	0.4	0.4	0.8	≤0.018	≤0.018	≤0.018	≤0.018	10	40	40	80
13	0.4	0.4	0.4	3.2	≤0.018	≤0.018	≤0.018	0.07	10	20	20	80
14b	0.4	0.4	0.8	0.8	0.07	0.07	0.07	0.15	10	20	20	80
15	0.2	0.4	0.4	0.4	≤0.018	≤0.018	≤0.018	0.15	2.5	10	10	20
16b	0.4	0.8	0.8	0.8	0.035	0.035	0.035	0.035	40	40	40	80
17b	0.2	0.4	0.4	0.4	≤0.018	0.035	0.035	0.035	40	40	40	80
18b	0.4	0.8	0.8	0.8	≤0.018	0.035	0.035	0.035	80	80	80	80
Geometric mean	0.25	0.37	0.43	1.37	≤0.02	≤0.03	≤0.03	≤0.06	12.0	28.2	28.2	≥54.4

^aMICs and MLCs are expressed in micrograms per milliliter. 

^bIsolate required 72 h of incubation prior to the initial MIC and MLC determinations. All other isolates had sufficient growth to read the first MICs and MLCs at 48 h.