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Analytical tools used for structural characterization and stability evaluation.
| Order of Characterization | Analytical Tools |
|---|---|
| Intact mass analysis | LC-ESI-QTOF |
| MALDI-TOF | |
| Higher Order (Secondary) | FTIR-ATR and Far UV-CD for secondary structure characterization |
| Product related Substances and Impurities | r and nrCE-SDS, size heterogeneity analysis |
| iCIEF, charge heterogeneity analysis | |
| Protein Concentration estimation | UV280 and RP-HPLC method |
| Aggregate Analysis | SEC-MALS |
