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. 2023 Aug 23;10(28):2302519. doi: 10.1002/advs.202302519

Figure 3.

Figure 3

Self‐healing electrical conductivity properties of hydrogels and replacement of bullfrog sciatic nerves by HASPy hydrogel ex vivo. A) The conductivity of HA and HASPy hydrogels (*p < 0.05, **p < 0.01, n = 3). B) Nyquist curves. C) Impedance spectra of HA and HASPy hydrogels. D) Schematic diagram of testing hydrogel cutting and self‐healing resistance. E) Resistance comparison of HA and HASPy hydrogels before and after self‐healing (*p < 0.05, **p < 0.01, n = 4). F) Schematic diagram of sciatic nerve replaced by HASPy hydrogel was accompanied by gastrocnemius contraction after electrical stimulation. G) The maximal tension T of the sciatic nerve replaced by HA hydrogel and the sciatic nerve replaced by HASPy hydrogel under different voltage stimulation (*p < 0.05, **p < 0.01, n = 3). H) Maximum tension of the gastrocnemius muscle after voltage stimulation of the original sciatic nerve, the sciatic nerve replaced by HA, self‐healing HA, HASPy, and self‐healing HASPy (*p < 0.05, **p < 0.01, n = 6). I) Nerve conductive time (CT) of the sciatic nerve, the sciatic nerve replaced by HA, self‐healing HA, HASPy, and self‐healing HASPy (*p < 0.05, **p < 0.01, n = 3).