Table 2.

Biopsy indications.

Indications for bone biopsy (May be more than one per patient), n (%)	95
Osteoporotic Male without Endocrine Abnormality (May also have another indication)	39 (41.1)
Parathyroidectomy Candidacy	29 (30.5)
Osteoporotic Pre-menopausal Female without Endocrine Abnormality (May also have another indication)	23 (24.2)
Decreasing BMD or fractures despite current or previous anti-osteoporotic treatment	20 (21.1)
Further Diagnostics i.e., atypical fractures, determine turnover for therapy guidance, rule out Hypophosphatasia	12 (12.6)
To diagnose Osteoporosis (potentially renal) vs Osteomalacia for potential treatment	7 (7.4)
Side effects/unable to tolerate current/previous treatment	4 (4.2)
Fractures despite low-to-normal bone density	4 (4.2)
Abnormal Lab Values Follow up	3 (3.2)
Diagnosed with Hypophosphatasia, turnover status if patient should remain on Teriparatide (Asfotase alfa not approved at the time)	1 (1.1)
Postpartum/lactation related osteoporosis (PLO)	1(1.1)
To determine treatment response (Only patient with 2 bone biopsies)	1 (1.1)