Table 5.
Clinical/treatment alterations guided by biopsy results.
Was there a major clinical/treatment alteration due to bone biopsy? (Removing Parathyroidectomy Candidacy), n (%) | 66 |
---|---|
No | 9 (13.6) |
Yes | 49 (74.2) |
Keep Treatment Course | 7 (10.6) |
Unknown (No Follow Up) | 1 (1.5) |
Those with No, why? n (%) | 9 |
Patient Status Declined | 5 (55.5) |
Normal Bone Histology | 1 (11.1) |
Teriparatide already used for 2 years, romosozumab not studied in transplant patients | 1 (11.1) |
Teriparatide recommended, but patient history of metastatic breast cancer and prior radiation treatment and therefore unknown risks | 1 (11.1) |
Patient did not want medication/treatment offered | 1 (11.1) |
Those with Yes or Keep Treatment Course (55), Did treatment align with histology recommendation? n (%) | 55 |
No | 6 (10.9) |
Yes | 45 (81.8) |
Anabolic therapy recommended, patient already completed 2 years of teriparatide treatment, IV zoledronic acid started instead | 1 (1.8) |
Antiresorptive therapy recommended, patient was already started on teriparatide, and patient was fracturing on actonel therefore teriparatide treatment kept | 1 (1.8) |
Anabolic therapy recommended, teriparatide only option at the time but patient did not want daily injections, therefore IV pamidronate started for 2 years with no improvement, patient eventually started and completed 2 years of teriparatide | 1 (1.8) |
No Treatment, but further diagnostics | 2 (3.6) |
Was there a major treatment alteration due to bone biopsy? (Including Parathyroidectomy Candidacy), n (%) | 95 |
No | 10 (10.5) |
Yes | 70 (73.7) |
Keep Treatment Course | 7 (7.4) |
Unknown (No Follow Up) | 8 (8.4) |
Those with No, why? n (%) | 10 |
Patient Status Decline | 6 (60) |
Normal Bone Histology | 1 (10) |
Teriparatide already used for 2 years, romosozumab not studied in transplant patients | 1 (10) |
Teriparatide recommended, but patient history of metastatic breast cancer and prior radiation treatment and therefore unknown risks | 1 (10) |
Patient did not want medication/treatment offered | 1 (10) |
Those with Yes or Keep Treatment Course (76), Did treatment align with histology recommendation? n (%) | 76 |
No | 6 (7.9) |
Yes | 66 (86.8) |
Anabolic therapy recommended, patient already completed 2 years of teriparatide treatment, IV zoledronic acid started instead | 1 (1.3) |
Antiresorptive therapy recommended, patient was already started on teriparatide, and patient was fracturing on actonel, therefore teriparatide treatment kept | 1 (1.3) |
Anabolic therapy recommended, teriparatide only option at the time but patient did not want daily injections, therefore IV pamidronate started for 2 years with no improvement, patient eventually completed 2 years of teriparatide | 1 (1.3) |
No Treatment, but further diagnostics | 2 (2.6) |