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. 2023 Sep 24;19:101715. doi: 10.1016/j.bonr.2023.101715

Table 5.

Clinical/treatment alterations guided by biopsy results.

Was there a major clinical/treatment alteration due to bone biopsy? (Removing Parathyroidectomy Candidacy), n (%) 66
No 9 (13.6)
Yes 49 (74.2)
Keep Treatment Course 7 (10.6)
Unknown (No Follow Up) 1 (1.5)
Those with No, why? n (%) 9
Patient Status Declined 5 (55.5)
Normal Bone Histology 1 (11.1)
Teriparatide already used for 2 years, romosozumab not studied in transplant patients 1 (11.1)
Teriparatide recommended, but patient history of metastatic breast cancer and prior radiation treatment and therefore unknown risks 1 (11.1)
Patient did not want medication/treatment offered 1 (11.1)
Those with Yes or Keep Treatment Course (55), Did treatment align with histology recommendation? n (%) 55
No 6 (10.9)
Yes 45 (81.8)
Anabolic therapy recommended, patient already completed 2 years of teriparatide treatment, IV zoledronic acid started instead 1 (1.8)
Antiresorptive therapy recommended, patient was already started on teriparatide, and patient was fracturing on actonel therefore teriparatide treatment kept 1 (1.8)
Anabolic therapy recommended, teriparatide only option at the time but patient did not want daily injections, therefore IV pamidronate started for 2 years with no improvement, patient eventually started and completed 2 years of teriparatide 1 (1.8)
No Treatment, but further diagnostics 2 (3.6)
Was there a major treatment alteration due to bone biopsy? (Including Parathyroidectomy Candidacy), n (%) 95
No 10 (10.5)
Yes 70 (73.7)
Keep Treatment Course 7 (7.4)
Unknown (No Follow Up) 8 (8.4)
Those with No, why? n (%) 10
Patient Status Decline 6 (60)
Normal Bone Histology 1 (10)
Teriparatide already used for 2 years, romosozumab not studied in transplant patients 1 (10)
Teriparatide recommended, but patient history of metastatic breast cancer and prior radiation treatment and therefore unknown risks 1 (10)
Patient did not want medication/treatment offered 1 (10)
Those with Yes or Keep Treatment Course (76), Did treatment align with histology recommendation? n (%) 76
No 6 (7.9)
Yes 66 (86.8)
Anabolic therapy recommended, patient already completed 2 years of teriparatide treatment, IV zoledronic acid started instead 1 (1.3)
Antiresorptive therapy recommended, patient was already started on teriparatide, and patient was fracturing on actonel, therefore teriparatide treatment kept 1 (1.3)
Anabolic therapy recommended, teriparatide only option at the time but patient did not want daily injections, therefore IV pamidronate started for 2 years with no improvement, patient eventually completed 2 years of teriparatide 1 (1.3)
No Treatment, but further diagnostics 2 (2.6)