Table 1.
Characteristics of studies included in the review.
| Author | Year | Country | Study Type | Age (Mean ± SD) | Follow-up years | No. Of participants | Confounders adjusted | NOS scores |
|---|---|---|---|---|---|---|---|---|
| Lin et al. | 2020 | China | Retrospective Cohort Study |
Underweight 67.02 ± 17.6 | 28-day | 7967 | age,sex, SOFA, mechanical ventilation on the first day, renal replacement therapy on the first day, congestive heart failure, cardiac arrhythmias, valvular disease, peripheral vascular disease, hypertension, other neurological diseases, chronic pulmonary disease, liver disease, renal failure, AIDS, lymphoma, metastatic cancer, solid tumor, diabetes, fluid and electrolyte disorders, alcohol abuse, drug abuse, and depression. | 8 |
| Normal 67.56 ± 16.88 | ||||||||
| Overweight 66.51 ± 16.21 | ||||||||
| Obese 63.71 ± 14.36 | ||||||||
| Weng et al. | 2020 | China | Prospective Cohort Study |
50.9 (±10.3) | 10 years | 440,763 | age, sex, study area、smoking status | 7 |
| Pepper et al. | 2019 | America | Retrospective Cohort Study |
NA | NA | 55,038 | patient, infection, and hospital-level factors | 7 |
| Zhou et al. | 2018 | China | Prospective Cohort Study | Survivors n = 104 | 90-day | 178 | NA | 7 |
| Non-survivors, n = 74 | ||||||||
| Wurzinger et al. | 2010 | Austria | Retrospective cohort study | Survivors 68 ± 15 |
NA | 301 | admission year, sex, age, presence of heart disease or chronic renal insufficiency, the number of pre-morbidities, origin of sepsis, and the simplified acute physiology score II | 7 |
| Non- survivors 76 ± 10 | ||||||||
| Zhang et al. | 2023 | China | Retrospective cohort study | Overweight 65.9 ± 17.0 |
1- year | 3145 | age, gender, SAPS, SOFA, diabetes, hypertension, coronary artery disease, congestive heart failure, atrial fibrillation, malignancy cancer, stroke, chronic obstructive pulmonary disease, renal disease, liver disease, MAP, creatinine, hemoglobin | 8 |
| Obese 62.9 ± 15.3 | ||||||||
| Tay-Lasso et al. | 2022 | America | Retrospective Cohort Study |
BMI<30 60 (64–85) |
1-year | 1246 | age, alcohol use, hypertension, congestive heart failure, diabetes mellitus, injury severity score, respiratory rate, pulse rate, systolic blood pressure, intensive care unit days, Glasgow coma scale. | 6 |
| BMI≥30 54 (60–80) | ||||||||
| Li et al. | 2019 | China | Retrospective Cohort Study |
Overweight,67.4 | 1-year | 5563 | Gender, Age, Marriage status | 8 |
| Obese,64.2 | ||||||||
| Gaulton et al. | 2014 | America | Retrospective Cohort Study |
Obese 60.6 (51.8–69) |
28-day | 1779 | ICU location and administration of a vasopressor | 7 |
| Non-obese 60.9 (49.2–71.9) | ||||||||
| Prescott et al. | 2014 | America | Prospective Cohort Study |
Overweight 78.7 ± 8.6 |
1-year | 1404 | age, race, gender, marital status, wealth, acute organ dysfunctions, ICU use, mechanical ventilation use, diabetes, other comorbidities, baseline cognitive status, and functional limitations. | 8 |
| Obese,75.3 ± 8.1 | ||||||||
| Huttunen et al. | 2007 | Finland | Retrospective Cohort Study |
NA | 30-day | 149 | alcohol abuse, age (continuous variable), sex, and causative organism | 7 |
| Arabi et al. | 2013 | Saudi Arabia | Retrospective Cohort Study |
Overweight,63.5 ± 15.9 | 12-year | 2882 | baseline characteristics and sepsis interventions | 7 |
| Obese,62.2 ± 14.6 |