Table 3.
Diagnostic accuracy of lactate, procalcitonin, NEWS score, NEWS + L score, qSOFA score and qSOFA + PCT score in predicting severe pneumonia.
| AUROC (95% CI) | p | ICF | +LR | -LR | |
|---|---|---|---|---|---|
| Lactate (mmol/L) | 0.552 (0.480–0.622) | 0.221 | |||
| PCT (ng/mL) | 0.685 (0.610–0.760) | 0.038 | 0.38 | 2.05 (1.4–3) | 0.57 (0.44–0.74) |
| NEWS | 0.658 (0.582–0.733) | <0.001 | 6 | 3.24 (1.61–6.52) | 0.74 (0.64–0.86) |
| qSOFA | 0.686 (0.613–0.759) | 0.037 | 1 | 3.04 (1.8–5.13) | 0.58 (0.47–0.72) |
| NEWS + L | 0.665 (0.589–0.740) | 0.038 | 4.5 | 1.56 (1.18–2.05) | 0.54 (0.39–0.76) |
| qSOFA + PCT | 0.758 (0.691–0.825) | 0.034 | 2 | 4.94 (2.51–9.72) | 0.54 (0.44–0.66) |
qSOFA: Quick Sequential Organ Failure Assessment; PCT: Procalcitonin; qSOFA + PCT: Combination of Procalcitonin and qSOFA; NEWS: National Early Warning Score; NEWS + L: Combination of NEWS and Lactate; ICF: Ideal Cut-off Value; + LR: Positive Likelihood Ratio; -LR: Negative Likelihood Ratio; CI: Confidence Interval.