Table 3.
ASA* at any time during pregnancy unadjusted for other RF N = 523 |
ASA at any time during pregnancy adjusted for other RF N = 523 |
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Risk Factor | n | % No ASA Rx | % ASA Rx | unadj OR | 95% CI | p value | adj OR | 95% CI | p value | |
High Risk | History Preeclampsia | 36 | 25 | 75 | 14.56 | 6.6, 32.11 | < 0.001 | 20.81 | 8.51, 50.87 | < 0.001 |
Chronic Hypertension | 33 | 21.21 | 78.79 | 17.908 | 7.52, 42.61 | < 0.001 | 13.57 | 5.05, 36.49 | < 0.001 | |
Pregestational Diabetes | 20 | 55 | 45 | 3.24 | 1.31, 8.05 | 0.011 | 1.69 | 0.51, 5.54 | 0.385 | |
Chronic Kidney Disease | 2 | 100 | 0 | omit | omit | |||||
Autoimmune Disease | 14 | 78.57 | 21.43 | 1.02 | 0.28, 3.72 | 0.974 | 0.97 | 0.186, 5.04 | 0.972 | |
Multifetal gestation | 7 | 71.43 | 28.57 | 1.52 | 0.291, 7.95 | 0.619 | 3.18 | 0.534, 18.99 | 0.204 | |
Mod. Risk | Advanced Maternal Age | 107 | 68.22 | 31.78 | 2.05 | 1.27, 3.301 | 0.003 | 2.79 | 1.51, 5.17 | 0.001 |
Black race | 167 | 67.07 | 32.93 | 2.63 | 1.71, 4.04 | < 0.001 | 2.52 | 1.48, 4.28 | 0.001 | |
Obesity | 257 | 76.26 | 23.74 | 1.344 | 0.882, 2.04 | 0.168 | 1.1 | 0.663, 1.84 | 0.701 | |
Family history Preeclampsia | 6 | 33.33 | 66.67 | 7.66 | 1.38, 42.399 | 0.02 | 5.49 | 0.797, 37.81 | 0.084 | |
> 10 year pregnancy interval | 22 | 68.18 | 31.82 | 1.78 | 0.707,4.48 | 0.22 | 2.73 | 0.983, 7.60 | 0.054 | |
Nulliparity | 68 | 64.71 | 35.29 | 2.307 | 1.33, 3.99 | 0.003 | 2.9 | 1.46, 5.76 | 0.002 |
Abbreviations: ASA, Aspirin; RF, Risk Factors