Table 1.

Patient’s and perioperative characteristics in MLOP (multimodal low-opioid anesthesia protocol) and ROP (routine-opioid anesthesia protocol) group

Parameters		MLOP group (n = 60)	ROP group (n = 60)	p-value
Age, years		60 (56; 63)	59 (54; 62)	0.419
Sex, n (%) - men - women		44 (73.33%) 16 (26.67%)	42 (70.00%) 18 (30.00%)	0.408
Body weight, kg		95.7 ± 16.1	98.6 ± 17.3	0.345
EuroSCORE II, %		3.00 ± 1.20	3.20 ± 1.3	0.390
NYHA FC > 2 > 3		27 (45.00%) 33 (55.00%)	24 (40.00%) 36 (60.00%)	0.428
LV EF, %		46.52 ± 8.06	47.18 ± 9.61	0.681
EDV, ml		147.48 ± 20.14	145.15 ± 21.17	0.537
MI, n (%)		13 (21.67%)	11 (18.33%)	0.741
PCI, n (%)		9 (15.00%)	8 (13.33%)	0.886
AH, n (%)		40 (66.67%)	42 (70.00%)	0.723
RCA dominance, n (%)		49 (81.7%)	54 (90.0%)	0.190
CA lesion n(%)	LCMA	16 (26.7%)	22 (26.7%)	0.239
	LCA	43 (71.7%)	36 (60.0%)	0.177
	LAD	47 (78.3%)	41 (68.3%)	0.215
	RCA	38 (63.3%)	46 (76.7%)	0.111
Initial Hb, g/dL		11.9 ± 1.31	12.4 ± 1.25	0.064
Duration of operation, min		192.83 ± 14.90	194.80 ± 14.16	0.460
Duration of anesthesia, min		221.95 ± 16.61	224.88 ± 18.30	0.360
Number of anastomoses: − 2, n (%) − 3, n (%)		26 (43.33%) 34 (56.67%)	22 (36.67%) 38 (63.33%)	0.245
Duration of CPB, min		83.6 ± 12.2	83.7 ± 11.23	0.115
Duration of XCL, min		23.5 ± 5.8	25.2 ± 5.1	0.182
Needs or RBCM - 1 unit > 1 unit		22 (36.67%) 7 (11.67%)	18 (30.0%) 10 (16.67%)	0.512

Notes. FC—functional class; LV EF—left ventricular ejection fraction; EDV—end-diastolic volume; MI—myocardial infarction; PCI—percutaneous coronary interventions; AF—atrial fibrillation; AH—arterial hypertension, LMCA—left main coronary artery, LCA—left circumflex artery, LAD—left anterior descending, RCA—right coronary artery, XCL—cross-clamping; RBCM—red blood cell mass, CPB—cardiopulmonary bypass