Table 3.
Predictors of CRBSI of study participants at the Korle Bu Teaching Hospital, Accra, Ghana, 2021-2022
| Unadjusted Logistic Regression Model | Adjusted Logistic Regression Model | |||||
|---|---|---|---|---|---|---|
| uOR | 95% CI | P-value | aOR | 95% CI | P-value | |
| Age | 1.01 | 0.99 – 1.03 | 0.495 | 1.05 | 0.99 – 1.11 | 0.078 |
| Sex | ||||||
| Female | 1.00 | 1.00 | ||||
| Male | 1.48 | 0.74 – 2.93 | 0.264 | 5.74 | 1.24 – 26.55 | 0.025 |
| Haemodialysis initiation | ||||||
| Emergency | 1.00 | 1.00 | ||||
| Elective | 0.55 | 0.22 – 1.4 | 0.209 | 0.28 | 0.04 – 2.14 | 0.221 |
| Underlying cause of ESKD | ||||||
| Others | 1.00 | 1.00 | ||||
| Hypertension | 0.55 | 0.2 – 1.51 | 0.244 | 0.30 | 0.03 – 2.76 | 0.288 |
| Diabetes | 0.63 | 0.3 – 1.36 | 0.24 | 0.22 | 0.05 – 0.93 | 0.04 |
| Duration of MHD | ||||||
| <1year | 1.00 | 1.00 | ||||
| ≥1year | 0.34 | 0.13 – 0.88 | 0.026 | 0.07 | 0.01 – 0.62 | 0.017 |
| Frequency of MHD | ||||||
| <3times | 1.00 | 1.00 | ||||
| ≥3times | 0.61 | 0.19 – 2.01 | 0.417 | 0.24 | 0.02 – 2.77 | 0.254 |
| Catheter insertion site | ||||||
| Femoral Vein | 1.00 | 1.00 | ||||
| Jugular Vein | 1.05 | 0.49 – 2.28 | 0.894 | 0.89 | 0.15 – 5.26 | 0.896 |
| Regular clinic follow-up | ||||||
| No | 1.00 | 1.00 | ||||
| Yes | 1.05 | 0.49 – 2.28 | 0.894 | 0.66 | 0.14 – 3.12 | 0.604 |
| Previous CRBSI | ||||||
| No | 1.00 | 1.00 | ||||
| Yes | 1.53 | 0.6 – 3.93 | 0.372 | 6.61 | 0.57 – 76.97 | 0.132 |
| Hb(g/dl) | ||||||
| <10 Low | Low | 1.00 | ||||
| 10-12 Normal | 0.45 | 0.12 – 1.67 | 0.232 | 0.22 | 0.01 – 3.76 | 0.296 |
| >12 High | 0.90 | 0.08 – 10.22 | 0.929 | 1.29 | 0.05 – 35.86 | 0.879 |
| MCV (fL) | ||||||
| <75 Low | 1.00 | 1.00 | ||||
| 75-100 Normal | 0.80 | 0.33 – 1.92 | 0.617 | 1.96 | 0.28 – 13.82 | 0.498 |
| MCH (pg) | ||||||
| <25 Low | 1.00 | 1.00 | ||||
| 25-30 Normal | 0.59 | 0.28 – 1.23 | 0.16 | 0.20 | 0.03 – 1.49 | 0.117 |
| >30 High | 0.49 | 0.11 – 2.12 | 0.343 | 0.07 | 0.01 – 0.41 | 0.003 |
| Neutrophil count (x 109/L) | ||||||
| <2 Low | 1.00 | 1.00 | ||||
| 2-7 Normal | 0.38 | 0.08 – 1.72 | 0.207 | 0.01 | 0.001 – 0.12 | 0.001 |
| >7 High | 2.47 | 0.57 – 10.75 | 0.229 | 0.71 | 0.01 – 34.85 | 0.865 |
| Lymphocyte count (x 109/L) | ||||||
| <1 Low | 1.00 | 1.00 | ||||
| 1-3 Normal | 1.87 | 0.69 – 5.05 | 0.22 | 11.29 | 1.62 – 78.64 | 0.014 |
| >3 High | 1.19 | 0.24 – 5.99 | 0.835 | 0.85 | 0.07 – 10.73 | 0.901 |
| Platelet count (x 109/L) | ||||||
| <150 Low | 1.00 | 1.00 | ||||
| 150-400 Normal | 0.59 | 0.26 – 1.37 | 0.219 | 0.43 | 0.09 – 2.14 | 0.301 |
| >400 High | 1.34 | 0.45 – 3.96 | 0.597 | 2.58 | 0.35 – 19.07 | 0.353 |
uOR Unadjusted odds ratio, aOR Adjusted odds ratio, CI Confidence interval, HD means haemodialysis, ESKD means end-stage kidney disease, CRBSI means Catheter-related bloodstream infection, Hb means haemoglobin, MCV means mean corpuscular volume, MCH means mean corpuscular haemoglobin, g/dl gram per decilitre, fL Femtolitre, pg: picogram, L Litre