Table 2.

List of drugs approved by FDA for skin cancer treatment

Generic name	Trade Name	Dosage form	Mechanism of action	Indication	Side effects
Imiquimod	Aldara/ Zyclara	Cream/ ointment (topical)	Immune response modifier also treats genital and anal warts by enhancing the activity of the body’s immune system	Use to treat superficial basal cell carcinoma and actinic keratosis	Redness, itching, headache, diarrhea, Back pain, tiredness, etc
Vismodegib	Erivedge	Capsule (oral)	Works as hedgehog pathway inhibitor	Generally used to treat basal cell carcinoma and malignant melanoma, can’t be consumed by pregnant women	Muscle spasms, tiredness, joint pain, hair loss, weight loss, etc
Sonidegib	Odomzo	Capsule (oral)	Work as hedgehog pathway inhibitor	Commonly used to treat basal cell carcinoma and also that kind of skin cancer which are reoccur after the surgical or radial treatment and can’t be consumed by pregnant women	Diarrhea, abdominal pain, loss of appetite, nausea, vomiting, anemia, hair loss, etc
5-fluorouracil	Carac/ Efudex/ Fluoroplex/Tolac	Cream/ointment(topical)	It is a kind of antimetabolite that acts by killing fast-growing abnormal cells by inhibiting DNA formation	Generally used to treat actinic keratosis, and solar keratosis which were caused due to overexposure of UV rays by few years	Burning, crusting, redness, pain, discoloration, etc