Table 2.
Comparison of coronary lesion characteristics in the overall cohort stratified by lesion stenosis, and in the FFR-CT sub-group stratified by hemodynamic significance.
| Overall CT cohort (N = 532), stratified by stenosis group | |||
|---|---|---|---|
| Less than 50% Stenosis (n = 435) | Greater than or equal to 50% Stenosis (n = 97) | p-value | |
| Agatston calcification score | 213.3 ± 420.9 | 1295.8 ± 1310.9 | <0.001 |
| Percentile rank | 36.5 ± 33.6 | 76.9 ± 17.8 | <0.001 |
| Total atherosclerotic plaque volume (mm3) | 219.6 ± 270.4 | 764.4 ± 468.9 | <0.001 |
| Percent atheroma volume | 6.68 ± 6.6 | 21.23 ± 10.97 | <0.001 |
| Total calcified plaque (mm3) | 88.4 ± 164.6 | 400.2 ± 351.9 | <0.001 |
| Total non-calcified plaque (mm3) | 130.7 ± 146.1 | 366.4 ± 212.1 | <0.001 |
| Low density non-calcified plaque (mm3) | 1.6 ± 2.7 | 5.6 ± 7.8 | <0.001 |
| Non-calcified plaque (mm3) |
129.1 ± 144.9 |
360.8 ± 207.3 |
<0.001 |
| FFR-CT sub-group (n = 121) by hemodynamic significance | |||
| Not hemodynamically significant (n = 66) |
Hemodynamically significant (n = 55) |
p-value |
|
| Agatston calcification score | 540 ± 657 | 1353.3 ± 1324.1 | <0.001 |
| Percentile rank | 64.8 ± 25.4 | 79.6 ± 13.4 | <0.001 |
| Total atherosclerotic plaque volume (mm3) | 417.1 ± 396.2 | 770.8 ± 468.6 | <0.001 |
| Percent atheroma volume | 11.99 ± 7.25 | 21.3 ± 10 | <0.001 |
| Total calcified plaque (mm3) | 193 ± 209.9 | 425.6 ± 356.6 | <0.001 |
| Total non-calcified plaque (mm3) | 219.1 ± 234.9 | 349.3 ± 198.8 | 0.001 |
| Low density non-calcified plaque (mm3) | 2.4 ± 3.9 | 4.5 ± 5.7 | 0.02 |
| Non-calcified Plaque (mm3) | 216.7 ± 233.5 | 344.7 ± 194.8 | 0.002 |