TABLE 5.
IC50s for hydrolysis of benzylpenicillin
| Inhibitor | IC50
(μM)a
|
|
|---|---|---|
| TEM-1 | Asn276Asp | |
| Clavulanic acid | 0.02 | 0.13 |
| Sulbactam | 10 | 13.4 |
| Tazobactam | 0.15 | 0.33 |
| Brobactam | 0.02 | 0.03 |
a
The standard deviation for the analysis was ±5%.
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