Fig. 1.

Experimental Design: Mouse Models and BTZ Treatment. Schematic diagram of mouse genotypes and BTZ treatment: Wild type (WT) mice treated with vehicle, administered both i.p. and p.o. and hAPP mice treated according to one of three regimens: vehicle (i.p. and p.o.); BTZ (i.p.) and vehicle (p.o.); or BTZ (i.p.) and CSA (p.o.). After the treatment period, animals were euthanized, and tissue samples were collected